Man PAN

Man PAN is an Associate Professor at the School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University. His research focuses on the molecular mechanisms of ubiquitin-mediated protein quality control, with an emphasis on the development of chemical biology tools to study ubiquitination and deubiquitination processes. His work explores strategies for targeted protein degradation, including the design of ubiquitin-modified protein probes and PROTAC molecules. PAN is currently leading several research projects funded by the Shanghai Science and Technology Commission and the National Natural Science Foundation of China.

Pan, Man is a researcher at Shanghai Jiao Tong University with expertise in ubiquitination, proteostasis, and chemical biology. His work focuses on understanding the structural and functional aspects of ubiquitin chains and their roles in cellular processes. He has contributed to the development of chemical methods for protein synthesis and modification, including site-specific hydrazinolysis, native chemical ligation, and thiol–yne radical reactions. His research also explores the structural basis of ubiquitin modification and its implications in disease mechanisms. By combining chemical biology techniques with structural biology, Pan's studies provide insights into protein degradation, signaling pathways, and therapeutic applications.