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Linda Nicholson

Cornell University · Biology

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Linda Nicholson is a professor in the Department of Molecular Biology and Genetics at Cornell University. Her research focuses on the investigation of relationships between protein dynamics and function, including function in the context of the cell and/or organism. She uses NMR spectroscopy as a primary research tool to measure internal motions of individual bonds within a protein. Her studies have focused on proteins involved in disease processes, and she is currently expanding her dynamics studies into thermodynamics and kinetics to obtain a more complete picture of the energy landscape of proteins. She also serves as the Hays and James M. Clark Director of the Office of Undergraduate Biology.


Scholar profile summary
Scholar-generated biography

Linda K Nicholson is a Professor at Cornell University specializing in Biophysics, NMR, and Protein Structure and Dynamics. Her research focuses on understanding the structural and dynamic properties of proteins using nuclear magnetic resonance (NMR) techniques. She investigates the role of proline isomerization in protein function, particularly in the context of neurodegenerative diseases like Alzheimer's. Her work also explores the structural dynamics of proteins such as HIV-1 protease and amyloid precursor protein, with applications in drug design and understanding disease mechanisms. Her research integrates NMR spectroscopy with biochemical and biophysical methods to elucidate protein behavior at the atomic level.

Source: google_scholar · 99 words
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