Brian D. Gregory

Brian D. Gregory is a Professor of Biology at the University of Pennsylvania, Department of Biology. His research focuses on computational biology, genetics, epigenetics, genomics, and plant biology. His work explores mechanisms and regulation of RNA modifications in post-transcriptional regulation, including N6-methyladenosine and NAD+ caps. He uses genomic, bioinformatic, and systems biology approaches alongside molecular genetic and biochemical techniques to study these modifications in model organisms like Arabidopsis thaliana. Gregory also develops high-throughput sequencing methods to analyze RNA secondary structure and RNA-protein interactions. His research has been published in prominent journals such as Plant Cell and Cell Reports.

Brian D. Gregory is a Professor of Biology at the University of Pennsylvania, specializing in RNA biology, genomics, computational biology, and genetics. His research explores the molecular mechanisms underlying RNA metabolism, epigenetic regulation, and their roles in development and disease. He investigates how RNA modifications, such as N6-methyladenosine, influence gene expression and chromatin structure. His work also examines the interplay between RNA processing and epigenetic changes in processes like senescence and neurodegeneration. By integrating computational approaches with experimental models, Gregory contributes to understanding the complex regulatory networks governing cellular function.