Steven G. Clarke

Steven G. Clarke is a faculty member in the Department of Chemistry at the University of California, Los Angeles. His research focuses on Aging and Development, Biochemistry, Chemical Biology, Metabolism, Systems Biology, and Biological Regulation. His work explores the molecular mechanisms underlying cellular processes and their implications in health and disease. Professor Clarke's research contributes to understanding complex biological systems through interdisciplinary approaches. For more information, visit his profile page at https://www.chemistry.ucla.edu/directory/clarke-steven-g/.

Steven G. Clarke is a Professor of Chemistry and Biochemistry at UCLA, specializing in posttranslational modifications, particularly methylation, and biological aging. His research explores the role of protein arginine methylation in cellular processes and its implications for aging and disease. Clarke's work includes studies on enzymes involved in methylation, such as PRMT1 and PRMT5, and their impact on protein structure and function. He has also investigated the mechanisms of protein degradation through processes like succinimide formation and the role of posttranslational modifications in neurodegenerative diseases such as Alzheimer's. His research highlights the significance of methylation in regulating gene expression and cellular signaling.