Guillaume F. Chanfreau

Professor Guillaume F. Chanfreau is affiliated with the University of California, Los Angeles, in the Department of CHEM. His research interests include Aging and Development, Biochemistry, Chemical Biology, Development and Gene Regulation, Metabolism, Proteomics and Bioinformatics, Systems Biology and Biological Regulation. His profile page can be accessed at https://www.chemistry.ucla.edu/directory/chanfreau-guillaume-f/.

Guillaume Chanfreau's research focuses on the molecular mechanisms underlying RNA processing and degradation, particularly in the context of small nucleolar RNAs (snoRNAs) and group II introns. His work explores the roles of RNA endonucleases such as RNase III in the maturation of snoRNAs and the regulation of pre-mRNA splicing. Chanfreau has also investigated the structural basis of RNA recognition by proteins like Rnt1p and the functional implications of RNA tetraloop structures. His studies highlight the interplay between RNA structure, enzyme specificity, and cellular RNA metabolism, contributing to the understanding of RNA biology in yeast and other organisms.