Regular biography
XUE SHIFENG is an Assistant Professor in the Department of Biology at the National University of Singapore. He holds the NUS Presidential Young Professorship (PYP). His research interests are not explicitly detailed in the provided information. For further details, please visit his profile page at https://www.dbs.nus.edu.sg/staffs/xue-shifeng/ or contact him via email at dbsxues@nus.edu.sg.
Scholar-generated biography
Shifeng Xue's research focuses on the role of ribosomes in gene regulation and organismal biology, particularly through specialized ribosome activity and ribosome-mediated specificity in Hox mRNA translation. His work explores how RNA regulons in Hox 5′ UTRs confer ribosome specificity, influencing vertebrate tissue patterning. Additionally, Xue investigates the genetic and epigenetic mechanisms underlying developmental disorders, such as Bosma arhinia microphthalmia syndrome and facioscapulohumeral dystrophy, with a focus on SMCHD1 and its involvement in de novo methylation and chromatin architecture. His studies also address A-to-I RNA editing, cis-regulatory RNA elements, and the epigenetic regulation of DUX4, contributing to understanding the molecular basis of congenital syndromes and muscular degeneration.