Bruce Armitage

Bruce Armitage is a Professor and Department Head in the Department of Chemistry at Carnegie Mellon University. His research focuses on bioorganic and chemical biology, analytical chemistry, and polymer science. Armitage's work includes the design and synthesis of peptide nucleic acid (PNA) oligomers for biological imaging and sensing, as well as the development of fluorescent dyes and DNA nanostructures for advanced imaging technologies. He also teaches 'Hooked: The Molecular Basis of Addiction,' a course that explores the molecular and societal aspects of addiction. His research collaborations span multiple departments and institutions, and he is affiliated with the Center for Nucleic Acid Science and Technology.

Bruce A. Armitage is a researcher in bioorganic chemistry, focusing on the interaction of cyanine dyes with DNA and the development of fluorescent DNA nanotags. His work explores the self-assembly of helical cyanine dye aggregates on DNA and PNA templates, emphasizing supramolecular chain polymerization and DNA-templated formation. Armitage's research also investigates the photocleavage of nucleic acids, electron-transfer reactions, and the synthesis of fluorogenic cyanine dyes. His studies aim to enhance the photostability and fluorescence properties of dyes for applications in molecular recognition and DNA hybridization. These efforts contribute to the understanding of DNA structure, function, and the design of advanced molecular tools for biotechnology.