Regular biography
Hendrik van Veen is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. His research focuses on membrane transporters, enzyme mechanisms, bioenergetics, drug efflux, and drug recognition. He investigates multidrug transporters from various pathogenic microorganisms and human tumour cells, examining their structural diversity and conserved functions. His work explores biochemical and structural mechanisms of bacterial drug resistance, persistence, and tolerance. Techniques used include membrane protein purification, drug transport and binding essays, electrophysiology, and site-directed mutagenesis.
Scholar-generated biography
Hendrik W. van Veen is a researcher at the University of Cambridge, focusing on membrane transporters, molecular mechanisms, drug resistance, and antibiotics. His work explores the structure and function of multidrug efflux pumps, particularly in bacteria, and their role in antibiotic resistance. He investigates the molecular properties of bacterial multidrug transporters, including their ATP-binding cassette (ABC) mechanisms and interactions with various substrates. His research also examines the interaction of transporters with plant polyphenols and their implications in drug resistance. Van Veen's studies contribute to understanding the molecular basis of multidrug transport and its relevance to human health and microbial resistance.