Amanda Sferruzzi-Perri
Regular biography
Amanda Sferruzzi-Perri is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. She is a Professor in the Department of Physiology, Development and Neuroscience, and serves as Theme Lead for Reproduction, Development and Lifelong Health. Her research focuses on the environmental and genetic control of placental morphogenesis and function, with an emphasis on its relevance for fetal development, maternal health, and the long-term programming of disease. Her work explores pregnancy, the fetus, the placenta, developmental programming, and cardio-metabolic disease.
Scholar-generated biography
Amanda Sferruzzi-Perri's research focuses on the endocrine regulation of placental function and its impact on fetal growth. Her work explores how maternal metabolic and hormonal factors influence placental phenotype, nutrient allocation, and fetal development. Key areas include the role of insulin-like growth factors (IGFs), hypoxia inducible factors, and maternal diet in shaping placental adaptations. She investigates how placental efficiency and resource allocation are modulated by environmental and physiological conditions, with implications for pregnancy outcomes and fetal health. Her studies also examine the interplay between maternal metabolism, placental function, and fetal growth trajectories, particularly in response to stressors such as hypoxia and obesogenic diets.