Ritwick Sawarkar

Ritwick Sawarkar is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. He is a Group Leader in the Department of Genetics, Department of Pharmacology, Department of Biochemistry, and the MRC Toxicology Unit. His research focuses on how cells sense and respond to environmental stress through transcription, with specific interests in proteostasis, epigenetics, stress response, and chaperones. His work employs techniques such as chromatin biochemistry, RNA-seq, SILAC mass spectrometry, metabolome analysis, and genomics.

Ritwick Sawarkar is a researcher at the MRC Toxicology Unit, University of Cambridge, focusing on molecular mechanisms underlying cellular responses to stress and environmental stimuli. His work explores how proteins like Hsp90 regulate gene expression by interacting with paused RNA polymerase and chromatin. Sawarkar's research also investigates the role of ribosomal frameshifting, transcriptional downregulation, and nuclear condensation in stress responses. Additionally, he examines the impact of endogenous retroviruses, transposable elements, and heat-shock proteins on cellular processes such as DNA repair, transcription, and protein homeostasis. His studies integrate molecular biology, biochemistry, and computational approaches to uncover the functional significance of RNA-protein interactions and chromatin dynamics.