Regular biography
Jeanne Salje is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. Her research focuses on the fundamental biology of obligate intracellular bacteria, particularly Orientia tsutsugamushi, which causes scrub typhus. Her work explores animal-microbe interactions, host-pathogen cell biology, bacterial cell biology, and the Rickettsiales group. She utilizes techniques such as light microscopy, electron microscopy, and comparative genomics in her studies. Salje is also involved in collaborative research areas including arthropod research and symbiosis.
Scholar-generated biography
Jeanne Salje is a researcher at Cambridge University specializing in bacterial cell biology, particularly obligate intracellular bacteria such as Rickettsiales and Orientia tsutsugamushi. Her work explores the molecular mechanisms underlying bacterial survival and pathogenesis, including the role of bacterial actin and plasmid segregation systems. She investigates the unique biology of intracellular pathogens, focusing on their interactions with host cells and the development of novel tools for studying these genetically intractable organisms. Her research also addresses the structural and functional aspects of bacterial cell wall synthesis and the impact of these processes on host immunity and disease progression.