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Anna Philpott

Development Cancer Cell cycle Differentiation Neurogenesis

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Anna Philpott is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. She is a Professor of Cancer and Developmental Biology and serves as Head of the School of Biological Sciences. Her research focuses on mechanisms that control cell responses to fate challenges, as well as the coordination of cell cycling with stem cell maintenance and differentiation during development, homeostasis, and disease. Her work encompasses areas such as development, cancer, cell cycle, differentiation, and neurogenesis, employing techniques like embryology, transcriptomics, epigenetics, and single-cell genomics.


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Anna Philpott is a professor of Cancer and Developmental Biology at the University of Cambridge, focusing on the molecular mechanisms underlying cell cycle regulation and its role in neural development and cancer. Her research explores how cell cycle transitions coordinate with differentiation processes in the nervous system, particularly in the cerebral cortex and Xenopus retina. She investigates the function of cyclin-dependent kinase inhibitors, such as p27kip1 and p27Xic1, in promoting neuronal and glial cell fate decisions. Additionally, her work examines the role of nuclear chaperones and ubiquitylation in chromatin remodeling and DNA replication. Philpott's studies also address the developmental origins of brain tumors and the regulation of stem cell niches in the gastrointestinal tract.

Source: google_scholar · 114 words
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