Regular biography
Daniel Nietlispach is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Biochemistry. His research focuses on integral membrane proteins, particularly 7-helical membrane proteins such as microbial rhodopsin and the large family of eukaryotic G protein-coupled receptors (GPCRs). GPCRs are physiologically important membrane proteins at the cell surface that sense signalling molecules such as hormones and neurotransmitters and are the targets of a multitude of prescribed drugs. His work involves structural biology, membrane proteins, signalling at the membrane, mechanistic studies, and techniques such as NMR spectroscopy, atomic resolution information, molecular dynamics, and biophysics.
Scholar-generated biography
Daniel Nietlispach is a Professor of Biomolecular NMR at the University of Cambridge, specializing in the structural and functional analysis of biomolecules using NMR spectroscopy. His research focuses on GPCRs, membrane proteins, and cell signalling mechanisms, with an emphasis on understanding their structural dynamics and interactions. He has contributed significantly to the structural elucidation of various proteins, including HP1 chromodomains, Cdc42, and sensory rhodopsin II, using advanced NMR techniques. His work also explores the application of NMR in structural biology, particularly in the study of membrane proteins and their roles in cellular processes.