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Florian Merkle

Neuroscience Stem cell Disease modelling Neurodegeneration Obesity

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Florian Merkle is an Associate Professor in the Department of Pharmacology at the University of Cambridge. His research focuses on Neuroscience, Stem cell biology, Disease modelling, Neurodegeneration, and Obesity. Merkle utilizes human pluripotent stem cell-derived culture systems to investigate the mechanistic basis of human neurological diseases, with the goal of developing effective treatments. His work incorporates techniques such as confocal imaging, calcium imaging, behavioural phenotyping, single cell sequencing, and scalable assays. Merkle's research is part of the School of Biological Sciences at the University of Cambridge.


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Florian T Merkle is a researcher at the University of Cambridge, focusing on Obesity, Stem Cell Biology, Neuroscience, and Developmental Biology. His work explores the role of neural stem cells in adult brain development, including their origin, differentiation, and functional maturation. He investigates how stem cells contribute to neurogenesis, neural diversity, and disease modeling, particularly in conditions like ALS and FTD. Merkle's research also extends to human pluripotent stem cells, their genetic stability, and their potential in regenerative medicine. His studies highlight the importance of stem cell niches and their impact on CNS repair and synaptogenesis.

Source: google_scholar · 96 words
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