Laura Machesky

Laura Machesky is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Pharmacology. Her research focuses on cancer metastasis, cell migration, cell invasion, the actin cytoskeleton, and metabolism. She employs molecular cell biology, in vivo models, and advanced imaging to investigate how stresses and signaling in the tumor and microenvironment influence metastasis and the reawakening of disseminated cancer cells. Her work integrates techniques such as microscopy, 3D cell-based models, and live cell studies.

Laura Machesky is a researcher in the Department of Biochemistry at the University of Cambridge, focusing on cell biology with an emphasis on cell migration, actin cytoskeleton dynamics, and cancer metastasis. Her work explores the molecular mechanisms underlying actin polymerization and its regulation by proteins such as WASP, Arp2/3 complex, and profilin. She investigates how these processes contribute to cellular functions like phagocytosis, adhesion, and cytoskeletal reorganization. Her research also examines the role of small GTPases such as Rho and Rac in signaling pathways that influence cell behavior and metastatic potential.