Valeria Lulla
Regular biography
Valeria Lulla is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Pathology. Her research focuses on the replication and pathogenicity of intestinal RNA viruses, with a particular emphasis on astroviruses and enteroviruses. She investigates virus-host interactions, virus replication, and the role of RNA viruses in disease. Her work employs techniques such as reverse genetics, ribosome profiling, RNA sequencing, and intestinal organoid handling. Valeria's research also explores infection mechanisms in primary neuronal cell cultures with neuropathogenic RNA viruses.
Scholar-generated biography
Valeria Lulla is a researcher at the University of Cambridge with a focus on virology, particularly the study of alphaviruses and their interactions with host immune systems. Her work explores the molecular mechanisms of viral replication, immune evasion, and vaccine development. She has investigated the role of CD4+ T cells in Chikungunya virus (CHIKV) infection, the impact of TLR3 loss on CHIKV pathology, and the design of attenuated vaccine candidates. Her research also includes the molecular determinants of viral proteolytic activity, the function of nonstructural proteins in viral replication, and the development of virus replicon-based assays for neutralization studies. Lulla's work contributes to understanding viral pathogenesis and the development of therapeutic strategies against emerging viral threats.