Catherine Lindon
Regular biography
Catherine Lindon is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Pharmacology. Her research focuses on the regulation of the cell cycle in human cells through ubiquitin pathways, including protein degradation, PROTACs, and related processes. She employs techniques such as molecular cell biology, quantitative imaging, and degradation assays. Lindon's work explores the role of ubiquitination and its implications for biomolecular condensates and ubiquitin chain topology. Her research contributes to the development of PROTACs and other therapeutic strategies.
Scholar-generated biography
Catherine Lindon is a Research group leader at the University of Cambridge, specializing in molecular cell biology. Her research focuses on the regulation of cell cycle progression, particularly through the study of cyclin-dependent kinases (CDKs), anaphase-promoting complex/cyclosome (APC/C), and Aurora kinases. Her work explores how these proteins coordinate mitotic events, including centrosome function, proteolysis, and spindle reorganization. Lindon's studies also examine the role of ubiquitin-mediated degradation in controlling mitotic exit and the significance of Aurora-A in cancer. Her research integrates molecular and cellular approaches to understand the dynamics of protein interactions and their impact on cell cycle regulation.