Walid Khaled

Walid Khaled is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. His research focuses on cancer tumour initiation, development, stem cells, and the mammary gland. Khaled's work aims to deconstruct the molecular basis of breast cancer heterogeneity and identify regulators of mammary epithelial cell fate that drive tumour heterogeneity, with the goal of developing targeted therapeutics for breast cancer. His research areas include single cell genomics, proteomics, and organoids.

Walid Khaled's research focuses on mammary gland development, differentiation dynamics of mammary epithelial cells, and the role of genes such as BCL11A in lymphoid development and breast cancer. His work explores the molecular mechanisms underlying epithelial-to-mesenchymal transition, cytokine signaling in mammary gland development, and the impact of transcription factors like Stat6 on lineage balance. Additionally, Khaled investigates the biology of naked mole-rats, addressing myths and clarifying their unique biological traits. His studies integrate single-cell RNA sequencing to uncover transcriptional changes and cellular shifts in the mammary gland during lactation and tumorigenesis.