Charlotte Houldcroft
Regular biography
Charlotte Houldcroft is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. Her research focuses on virology, virus evolution, host-virus co-evolution, and DNA viruses. She investigates the evolution and diversity of double-stranded DNA viruses, including those that cause diseases ranging from respiratory infections to chronic nerve pain and cancer. Her work employs techniques such as genomics, fluorospot, target-enriched sequencing, and phylogenetics. She is interested in sequencing, particularly target enrichment and host depletion, as well as T cell immune responses to viral infection.
Scholar-generated biography
Charlotte J. Houldcroft is a researcher in the Department of Genetics at the University of Cambridge, specializing in infectious disease, immunology, genomics, and virology. Her work focuses on understanding the genetic and immunological aspects of viral infections, particularly SARS-CoV-2 and other pathogens such as cytomegalovirus and Epstein-Barr virus. She has contributed significantly to genomic surveillance studies, investigating the transmission dynamics, lineage evolution, and pathogenicity of viruses. Her research also explores the role of host genetics in viral infections and the impact of viral mutations on immune evasion and disease severity.