Florian Hollfelder

Florian Hollfelder is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Biochemistry. His research interests include chemical biology, protein engineering, enzymology, directed evolution, and stem cells. Hollfelder's work focuses on understanding the principles of molecular recognition in chemistry and biology, with an emphasis on describing, manipulating, and creating functional molecules. His research also involves techniques such as microfluidics, synthesis, kinetics, and single-cell transcriptomics. He is associated with medical biochemistry and collaborates with hospitals on research themes.

Florian Hollfelder is a researcher at the University of Cambridge, focusing on mechanism in chemical biology and protein engineering. His work integrates directed evolution, microfluidics, and 3D cell culture to explore biological processes. Hollfelder's research spans the development of microfluidic platforms for high-throughput screening, including microdroplet-based assays for enzyme evolution and single-cell analysis. His studies also address developmental biology, such as embryo model systems for gastrulation and organogenesis. By combining microfluidics with cell-based assays, he advances understanding of protein dynamics and enzyme promiscuity. His work emphasizes the application of microfluidic technologies in biological and chemical research, enabling precise control and analysis at the single-cell and molecular levels.