James Fraser

James Fraser is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. His research focuses on muscle electrophysiology, including skeletal and cardiac muscle, excitability, and arrhythmia. He investigates electrophysiological homeostasis and its role in cardiac arrhythmias and sudden cardiac death. His work employs techniques such as computer modelling, intracellular microelectrode recording, multielectrode array, and Langendorff perfusion. Fraser's research areas include muscle excitability disorders and related collaborative opportunities.

James A Fraser is a researcher at the University of Cambridge with a focus on cardiac and skeletal muscle electrophysiology. His work explores mechanisms underlying cardiac arrhythmias, sudden cardiac death, and the role of ion homeostasis in excitable cells. Fraser's research includes investigations into myocardial conduction velocity, arrhythmogenic substrates, and the impact of genetic mutations such as RyR2-P2328S on cardiac and skeletal muscle function. His studies also examine the interplay between cell volume, membrane potential, and intracellular ion concentrations in both cardiac and skeletal muscle tissues. Fraser's research contributes to understanding the electrophysiological basis of arrhythmias and their potential therapeutic targets.