Brian Ferguson

Brian Ferguson is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences and the Department of Pathology. His research focuses on viral immunity, vaccinology, comparative innate immunity, nucleic acid sensing, and oncolytic viruses. He investigates how cells detect and respond to viral infections, with implications for innate and adaptive immunity. His work incorporates techniques such as cell signalling, recombinant virus generation, mouse immunology, proteomics, and comparative genomics. Ferguson's research themes include vaccinology, innate immune responses in cancer, and comparative immunology.

Brian J Ferguson is a researcher in immunology and virology, focusing on the molecular mechanisms of innate immunity and viral immune evasion. His work explores how viruses manipulate host signaling pathways, such as NF-κB and IRF-3, to suppress immune responses and enhance virulence. He investigates the role of host proteins like DNA-PK and PML in DNA sensing and tumor suppression, as well as the impact of viral proteins on immune evasion. His research also addresses the interplay between the gut microbiota and antiviral immunity, highlighting the importance of host-pathogen interactions in disease pathogenesis.