Alex Cagan
Regular biography
Alex Cagan is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. His research explores evolutionary processes in somatic tissue, focusing on mutation and selection in healthy tissues and their relation to cancer and ageing. His work encompasses lifespan, aging, pollution, somatic evolution, and comparative genomics. Cagan employs techniques such as somatic mutations, clonal dynamics, laser-capture microscopy, and bioinformatics. His research interests include embryo screening, environmental monitoring using genomics, and comparative genomics of somatic evolution.
Scholar-generated biography
Alex Cagan is a researcher at the Wellcome Sanger Institute with a focus on genetics. His work explores the dynamics of somatic mutations in human tissues, including the esophagus, kidney, and bladder, and their implications for aging and disease. He investigates clonal evolution in hematopoiesis and the role of genetic diversity in species such as great apes and domesticated animals. His research also examines the mutational landscapes of somatic and germline cells, as well as the evolutionary forces shaping genetic variation in populations. Cagan's studies contribute to understanding the genetic basis of cancer, immune responses, and evolutionary adaptation.