Clare Bryant

Clare Bryant is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. Her research focuses on immunology, bacterial infection, innate immunity, pattern recognition receptors, and inflammasomes. She investigates how bacteria are detected by the host through pattern recognition receptors and explores the links between PRR recognition of allergen or toxic proteins and chronic inflammatory diseases such as allergies and Alzheimer’s disease. Her work employs multidisciplinary approaches, including quantitative imaging, macrophage infection, inflammatory signalling analysis, and in vivo bacterial infection studies.

Clare Bryant is a Professor of Innate Immunity at the University of Cambridge, specializing in the study of innate immune responses and their role in infectious and inflammatory diseases. Her research focuses on Toll-like receptors (TLRs), NOD-like receptors (NLRs), and Pattern Recognition Receptors (PRRs), with a particular emphasis on their involvement in detecting pathogens such as Salmonella. She investigates the molecular mechanisms underlying immune signaling, including inflammasome activation and the interplay between immune and endocrine systems. Her work has explored the impact of innate immunity on reproductive health and inflammatory disorders, contributing to the understanding of immune-mediated diseases.