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Michael Boemo

Genome stability Cell cycle regulation DNA replication

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Michael Boemo is a Fellow at the University of Cambridge, affiliated with the School of Biological Sciences. His research focuses on genome stability, cell cycle regulation, and DNA replication. He develops computational methods and software to investigate how dysregulation of cell cycle mechanisms can lead to genome instability and cancer. His work incorporates mathematical modelling, artificial intelligence, high-performance computing, and software development. Boemo's research spans multiple disciplines, integrating computational and biological approaches to address complex questions in genetics and pathology.


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Michael A. Boemo is an Assistant Professor in the Department of Pathology at the University of Cambridge, specializing in DNA replication, Genome Stability, and Computational Biology. His research explores the dynamics of genome replication, focusing on how replication stress influences DNA copy number alterations and chromosome-scale losses. Boemo employs computational methods, including deep learning, to analyze nanopore sequencing data and detect replication fork dynamics. His work also investigates the formal modeling of biological systems and the role of DNA replication timing in genome structure and function. By integrating computational biology with molecular mechanisms, Boemo aims to uncover the principles governing genome stability and replication fidelity.

Source: google_scholar · 105 words
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