David James
Regular biography
Professor David James is affiliated with The University of Sydney's BIO department. His research interests include systems biology, signal transduction, protein trafficking, proteomics, cell metabolism, analytical biochemistry, cell development, proliferation and death, gastroenterology, hepatology, endocrinology, and clinical sciences. He is associated with the Charles Perkins Centre and has held positions at the Garvan Institute and the IMB University of Queensland. His work focuses on understanding metabolism and its regulation by factors such as insulin and exercise, with recent emphasis on systems biology and gene-environment interactions in metabolic disease.
Scholar-generated biography
David E James is a researcher at The University of Sydney specializing in systems biology, cell biology, and diabetes. His work explores the molecular mechanisms underlying glucose transport and insulin resistance, with a focus on the regulation of the glucose transporter GLUT4. He investigates how cellular signaling pathways, such as AMP-activated protein kinase (AMPK), influence metabolic processes in diabetic and insulin-resistant states. His research also examines the role of extracellular vesicles in intercellular communication during exercise and the impact of diet on insulin sensitivity. James's studies contribute to understanding the molecular landscape of insulin resistance and its implications for metabolic disorders.