Arthur Conigrave

Professor Arthur Conigrave is affiliated with The University of Sydney's BIO department. His research interests include receptors and membrane biology, basic pharmacology, clinical pharmacology and therapeutics, cell physiology, systems physiology, biochemistry and cell biology, pharmacology and pharmaceutical sciences, signal transduction, and medical physiology. His work focuses on the sensing of nutrients and mineral ions, particularly calcium and phosphate, with an emphasis on the Calcium Sensing Receptor (CaSR) signaling mechanisms. He is also involved in the study of gut hormone release and has contributed to the field through his research and academic leadership roles.

Arthur D Conigrave's research focuses on nutrient-sensing mechanisms, particularly the role of class C GPCRs in calcium and macronutrient metabolism. His work explores how these receptors mediate physiological responses to amino acids, phosphate, and calcium, with implications for bone health, parathyroid hormone secretion, and metabolic homeostasis. Conigrave's studies also investigate the structural and functional properties of the calcium-sensing receptor (CaSR), including its signaling pathways and interactions with allosteric modulators. His research highlights the interplay between dietary protein, amino acid sensing, and calcium metabolism, contributing to understanding metabolic compartmentation and gastrointestinal nutrient balance.