Alyson Ashe

Alyson Ashe is an Associate Professor in the Department of BIO at The University of Sydney. Her research focuses on epigenetics, including genome methylation and epigenomics, as well as genetics. She employs genetic engineering, microscopy, bioinformatics, and structural biology techniques to study epigenetic gene regulation across species. Ashe completed her undergraduate degree in Molecular Biology and Genetics at the University of Sydney and her PhD at the University of Sydney and the Queensland Institute of Medical Research under Prof Emma Whitelaw. She later worked as a postdoctoral research fellow at The Gurdon Institute in Cambridge, UK, before returning to The University of Sydney. Her work aligns with the Faculty of Science Research Strengths.

Alyson Ashe, affiliated with the University of Sydney, is a researcher whose work focuses on epigenetics, histones, and small RNA mechanisms. Her research explores how epigenetic processes, particularly through histone modifications and small RNA pathways, influence transgenerational inheritance and germline epigenetic memory. Ashe's studies often use model organisms such as Caenorhabditis elegans to investigate the role of small RNAs in antiviral immunity, chromatin regulation, and the interplay between viral and endogenous RNA in gene expression. Her work also examines the impact of epigenetic modifiers on developmental processes and phenotypic noise. Through experimental and genomic approaches, Ashe contributes to understanding the molecular basis of epigenetic inheritance and its implications for evolution and disease.