Yann Barrandon

Yann Barrandon is a Professor Emeritus at École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the BIO department. His research focuses on stem cell dynamics, particularly in stratified epithelia such as skin, esophagus, and the ocular surface. He has contributed to the characterization of skin diseases and gene therapy for dystrophic epidermolysis bullosa. Barrandon has also explored the role of microenvironmental variations in stem cell behavior and the potential of stem cells for epithelial cell therapy. His work includes pioneering studies on epidermal stem cell transplantation and the development of a fibrin matrix for clinical applications. He has been involved in several European stem cell consortia and has organized international conferences on stem cell research.

Yann Barrandon is a Professor Emeritus at Ecole Polytechnique Fédérale de Lausanne, specializing in biology with a focus on wound repair, stem cell biology, and epithelial regeneration. His research explores the mechanisms of keratinocyte proliferation, hair follicle morphogenesis, and the role of stem cell niches in tissue renewal. Barrandon's work includes studies on Netherton syndrome, desmoglein 1 degradation, and the regulation of epidermal growth factors. His contributions highlight the importance of clonal analysis, stem cell multipotency, and the interplay between signaling pathways like Hedgehog in hair development. His research has advanced understanding of epithelial regeneration and stem cell dynamics in skin and hair follicles.