Regular biography
Wouter Richard Karthaus is a PhD program committee member at the École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the BIO department. His role involves overseeing doctoral programs within the Molecular life sciences doctoral program. He can be contacted via email at wouter.karthaus@epfl.ch or through his profile page at https://people.epfl.ch/wouter.karthaus?lang=en. His research interests and additional details are not specified in the available information.
Scholar-generated biography
Wouter Karthaus is a researcher focused on cancer research, particularly in prostate cancer, with an emphasis on stem cell biology, endocrine therapy resistance, and organoid technology. His work explores mechanisms of lineage plasticity, antiandrogen resistance, and the role of signaling pathways such as Wnt and JAK/STAT in prostate cancer progression. Karthaus utilizes patient-derived organoid cultures to model rare prostate cancer phenotypes and study individual responses to therapies. His research also investigates the tumor microenvironment and genetic mutations, such as FOXA1 and ERF, that influence therapeutic response and oncogenesis. Karthaus' contributions span both basic and translational research in cancer biology.