Michele De Palma

Michele De Palma is an Associate Professor in the School of Life Sciences at École Polytechnique Fédérale de Lausanne (EPFL), Department of BIO. His research focuses on tumor resistance to immunotherapy mediated by myeloid cells and the angiogenic vasculature, as well as the development of novel platforms for engineered dendritic cell therapies. De Palma's work leverages cell engineering technologies and preclinical trials in genetically engineered mouse models of cancer to advance understanding of the tumor microenvironment. He teaches cancer biology and has received several awards, including the Robert Wenner Prize for cancer research in 2017. His research also explores the clinical potential of dendritic cell therapies and the taxonomy of Scarab beetles in the family Cetoniinae.

Michele De Palma is an Associate Professor of Life Sciences at EPFL, specializing in Cancer Immunology, Angiogenesis, Dendritic cells, and Cell Therapy. His research focuses on understanding the role of the tumor microenvironment in angiogenesis and how it influences cancer progression and therapeutic responses. De Palma's work explores the regulation of tumor angiogenesis by proangiogenic monocytes and pericyte progenitors, as well as the impact of macrophage polarization on tumor responses to anticancer therapies. He investigates strategies to enhance cancer immunotherapy through dendritic cell vaccines and the targeting of angiogenic pathways such as the ANG2/TIE2 axis. His research also examines the therapeutic potential of genetically modified hematopoietic stem cells in tumor treatment.