Regular biography
Dr. Michel Aguet, MD, is a Professor Emeritus at the École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the School of Life Sciences. His research has focused on molecular biology, including interferons and prion-related proteins, as well as the role of BCL9 proteins in stem cell regulation. He previously held academic and industry positions, including at the University of Zürich and Genentech. Aguet was also involved in directing the National Center of Competence in Research (NCCR) in Molecular Oncology. His laboratory is now closed due to retirement.
Scholar-generated biography
Michel Aguet is a researcher at the Ecole Polytechnique Fédérale de Lausanne (EPFL) with a focus on interferon signaling, prion research, developmental pathways in cancer, and cancer cell differentiation. His work explores the role of interferons in antiviral defense and tumor surveillance, as well as the functional significance of prion proteins in disease resistance. Aguet's studies also investigate genetic mechanisms underlying cancer progression and cellular differentiation, including the impact of signaling pathways like Notch and JAK-STAT. His research contributes to understanding immune responses and the molecular basis of diseases such as cancer and prion disorders.