Denis Duboule

Denis Duboule is a Professor Emeritus at École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the BIO department. He holds a PhD in mammalian embryology from the University of Geneva, obtained in 1984. His research focuses on embryology, genetics, and developmental genomics of mammals, particularly the structural and functional studies of mammalian Hox genes using mouse molecular genetic approaches. Duboule has been associated with the laboratory of Developmental Genomics (UpDUB) at EPFL since 2006. He is also active in science communication and is a member of several academies in Switzerland, France, and the Netherlands. He is a foreign member of the Royal Society (UK) and the National Academy of Sciences USA.

Denis Duboule is a Professor of Genetics at Collège de France, Paris, and affiliated with EPFL Lausanne and the University of Geneva. His research focuses on life sciences, particularly the regulation of gene expression during development and evolution. Duboule's work explores the molecular mechanisms underlying the spatial and temporal control of Hox genes, which are critical for body plan formation. He has extensively studied the colinearity of Hox gene clusters, their regulatory landscapes, and their role in limb development and heterochrony. His research also extends to circadian rhythms and the structural organization of homeotic genes, contributing to our understanding of developmental genetics and evolutionary biology.